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Engineering a protein to prevent brain damage from toxic agents Posted: 31 Jul 2014 06:51 AM PDT New research may help prevent brain damage for those exposed to pesticides and chemical weapons. The work centers on proteins called phosphotriesterases, which are able to degrade chemicals known as organophosphates -- found in everything from industrial pesticides to sarin gas. They permanently bond to neurotransmitters in the brain, interfering with their ability to function and causing irreversible damage. The researchers re-engineered the protein to make it sufficiently stable to be used therapeutically. |
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